Straight out of the '06 Buell Blast Manual. You can access them free on Buell.com by signing up which is also free.
[up] Off the top of my head, replace plug, clean carb, check fuel filter.
Starts But Runs Irregularly or Misses
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1. Spark plug in bad condition or partially fouled.
2. Spark plug cable in bad condition and leaking.
3. Spark plug gap too close or too wide.
4. Battery nearly discharged.
5. Damaged wire or loose connection at battery terminals or coils.
6. Intermittent short circuit due to damaged wire insulation.
7. Water or dirt in fuel system, filter or carburetor.
8. Fuel vent system plugged. See dealer.