Welcome to the forum
As this is your first post I'll let you know this has been posted 1000X's before.....:upset: If you do a short search, it will net you the typical results of that being a poor and unsuccessful choice. On rare occasions it's been lucky. Are you feeling lucky? Well, punk? Are you? (Sorry, my Dirty Harry came out:eagerness

lol.
Do you have any diagnostic tools? Are you familiar with motorcycle mechanics? If you aren't, you should take it to a V-twin shop and have it looked at.
If you are, (and posting your firmware version says you at least have access to tuning software) we can help you diagnose what's actually wrong with your Buell. It may actually be tuning and we can help you there too, but proper diagnosis will be faster, cheaper, and MUCH less frustrating for you and the strangers you just asked for help. You're welcome:eagerness:
What
precisely is the bike doing when it "isn't running great"?
Mileage?
New to you?
New problem?
Any recent mods?
Whats your girlfriend look like?
Whats your current AFV?
Have you messed with the tuning map or ECM parameters?
BUE2D is a very common firmware. The (probably custom) GPR can on the bike isn't. I would think a typical 'race tune' should be close enough to run well. If you insist on playing tuning roulette, check out Buelltooth.com for BUE2D maps and a .pdf service manual download.
Note that those maps come from other peoples bikes and in that format you also get their ECM parameters. Make sure to set yours back to where you want them.