The thing to watch out for anytime you're cutting plastic with power tools is the heat it's creating. I know they make specific tools to cut plexiglass, but every time I try to use it for something I get impatient and try to use a jigsaw for it. It cuts it, melts it, and it bonds back together right after the blade is through it, and by then it looks like a mess. I do the same thing every time. Just make sure you move slowly and take your time. If you use a dremel or something like that I'd use it on the slowest speed that seems productive so you get a nicer cut, and just plan to spend some time sanding when you're done.