The motorcycle engine for the harley is for a large bike, the Buells are based on the Sportster engine, and it is difficult to put anything larger in our frames as it is. The Coates Valve technology has been around in development for over 15 years as stated in the video, it would be interesting, to see other versions. I remember when they announced this idea way back in the Nineties, What have they been doing? It doesn't take 15 years to go through the Patent Process. The V-8 that they show in the video, is vibrating so bad it looks as if the headers would fracture and fail after several miles. If I wanted a Buell that Vibrated More than what I have Now I would Just Buy a Blast, come to think of it, the Coates engine would probably fit in that, Not Sure Though. They keep blaming all the emissions on the Poppet Valve engine, when in fact it is the tuning of the engine, the stoicometric Fuel/Air Ratio of 14.7 to 1, that gives you the best exhaust emissions, any leaner and the NOx go up, any richer the CO's go up, if it has a miss then the HC's go up. It is all a balance, the engine doesn't care what type of valve the mixture came through.
If that where the case, we would all be riding and driving around with 2 stroke engines, they have a much higher volumetric efficiency, ie Power every revolution. The problem with them is the emissions, for most of the 2 stroke designs you have the lubrication component, that gets into the combustion cylinder, which throws the HC's out of Wack.
As far as being able to use any fuel, nearly any engine can do that now also, just takes getting the tuning correct. The energy in Ethanol or Methanol is about 1/3 to 1/2 that of Gasoline, so its fuel /air ratio would need to be adjusted to compensate for the difference.
My Two Cents
Later