Depends what you do to it, even a stock set up, tuned up with some carb and exhaust mods, really improves the Blasts basic abilities to such an extent that the quote "It seems like a new bike..." is often repeated.
EZ's Stock bike Mods:
1)Drill a 1 5/8" hole directly across from the first hole of the stock exhaust on the same side as the stock hole but all the way to the right of it.
2)Rejet 45/170 (some years will have 170 stock - some don't)
3)Shim needle to 0.05 - 2 #4 machined brass washers is close.
4)Do the air box Mod - mild or wild - still keeping the basic look though.
5)Drill air-screw plug out, and bottom screw then turn 2 2/3 turns out.
6)Do primary adjustment - preferably sound method - on the loose side.
7)Make a splitter or buy one -
http://scaryfastracing.net/harley.html - see carb tkv.
8)Buy an Yost Tube and put it in your carb - Ebay has them cheap for a CV40 - 2000 era - discard the rest of kit.
Eight simple things to increase the delivery of power on a Buell Blast - making it even more of a Blast to ride!
EZ
Jetting for a V&H would be 45/175 - rest the same.
EZ